In stage 2, all the subjects who reported symptoms suggestive of asthma or chronic bronchitis (CB), a random sample (30%) of the subjects who reported rhinitis and a random sample (40%) of the subjects who did not report respiratory symptoms, diagnoses or hospitalizations were invited to clinics, where they underwent interviews and clinical tests. ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. Standard Reference for the Six-Minute-Walk Test in Healthy Children Instructions:1,2 Please refer to the protocol for standardized administration of the 6MWT. In our analysis, only the subjects eligible for the 6-min walking test (6MWT) protocol were considered. de Marco R, Accordini S, Antonicelli L, Bellia V, Bettin MD, Bombieri C, Bonifazi F, Bugiani M, Carosso A, Casali L, Cazzoletti L, Cerveri I, Corsico AG, Ferrari M, Fois AG, Lo Cascio V, Marcon A, Marinoni A, Olivieri M, Perbellini L, Pignatti P, Pirina P, Poli A, Rolla G, Trabetti E, Verlato G, Villani S, Zanolin ME. The 6 minute walk test calculator provides reference values for the distance an adult should walk during six minutes. Respir Med. To do that, they took measurements from 117 healthy men and 173 healthy women, aged 40 to 80 years. Pinto-Plata VM, Cote C, Cabral H, Taylor J, Celli BR. LC, MEZ, GD, PF, LGDC, EC, MAA, MO, GV and MF contributed to the interpretation of data, revised the paper critically for important intellectual content and approved the version to be published. Would you like email updates of new search results? Accessibility Lines represent fitted spline regression with 95% confidence interval of the mean. The study was approved by the Faculty of Kinesiology, University of Zagreb, Croatia. The strength of the study is that participants were a large sample from the general population, represented all age groups and were well balanced by sex. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. R34 HL136989/HL/NHLBI NIH HHS/United States, T32 HL087738/HL/NHLBI NIH HHS/United States, U01 HL125212/HL/NHLBI NIH HHS/United States, UL1 TR002243/TR/NCATS NIH HHS/United States. 2014;90(3):2507. Factors the decrease and increase the 6MWT result: Let's see how the 6 minute walk test calculator works using an exemplary patient. The informed consent voluntarily was signed by the participants, participants parents or their guardians. When the sample of subjects meeting the inclusion criteria to be defined as healthy was obtained, two multivariable linear models were fitted to data. DOC Table of Contents: - University of Missouri This statement provides practical guidelines for the 6-minute walk test (6MWT). Before the testing, physical education teachers responsible for undertaking the tests in each school were briefly instructed about the measurement procedures. Therefore, future research should be performed for each country to determine normative data for the 6MWT in the pediatric population, regarding testretest reliability and validity properties (the associations between the 6MWT and health-related outcomes). We explored whether these equations apply to CHF patients. 2023 Apr 12;11(8):1106. doi: 10.3390/healthcare11081106. Please enable it to take advantage of the complete set of features! 2023 BioMed Central Ltd unless otherwise stated. Repeat 6MWD was surprisingly variable, with a median difference between tests of 32.5 31.9 m. Established reference equations performed poorly in this population, largely because age has much less effect on 6MWD in this group than in older adults. We compared our results with those of Enright and Sherrill [14], a study similar to our own as conducted in a large general population sample, although with a smaller age range of participants. A 6 minute walk test is a submaximal exercise test that measures the distance walked over the span of 6 minutes. [20], who based their categorisation on earlier publications [21, 22]: subjects who performed physical activity with a frequency of 23 times a week or more and with a duration of about 1h a week or more were classified as active, the remaining subjects as not active. Part of Shaaban R, Leynaert B, Soussan D, Anto JM, Chinn S, de Marco R, Garcia-Aymerich J, Heinrich J, Janson C, Jarvis D, Sunyer J, Svanes C, Wjst M, Burney PG, Neukirch F, Zureik M. Physical activity and bronchial hyperresponsiveness: European Community Respiratory Health Survey II. Leach RM, Davidson AC, Chinn S, Twort CHC, Cameron IR, Bateman NT. Six-minute walk test: reference values and prediction equation in In 102 healthy Caucasians, 20-50 years old, we investigated the effect of anthropometrics on the 6-min walk test (6MWT), in order to provide reference values for walk distance (6MWD), oxygen saturation (SpO 2 ), pulse rate (PR), respiratory rate (RR), breathlessness perception (VAS) and for the walking distance and body weight . 1982;284:16078. The participants were distributed by age range as follows: 155 (29.3%) were young (<39 yrs), 332 (62.6%) were middle-aged (4064 yrs) and 43 (8.1%) were elderly (6578 yrs). Results: 2019 Mar-Apr;25(2):83-89. doi: 10.1016/j.pulmoe.2018.04.003. Am J Respir Crit Care Med. Weight negatively affects the distance travelled in females, but not in males; additionally, self-reported physical activity appears to be associated with 6MWD only in women; finally, an interaction between age and height was seen exclusively in men. 500 Meters Is a Result of 6-Minute Walk Test Which Differentiates Patients with High and Low Risk of Postoperative Complications after LobectomyA Validation Study - PMC ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Holmen TL, Barrett-Connor E, Clausen J, Holmen J, Bjermer L. Physical exercise, sports, and lung function in smoking versus nonsmoking adolescents. Six-minute walk distance in healthy subjects: reference standards from a general population sample. Cahalin L, Pappagianopoulos P, Prevost S, Wain J, Ginns L. The relationship of the 6-min walk test to maximal oxygen consumption in transplant candidates with end-stage lung disease. Bland-Altman plot of change in six-minute walk distance (6MWD) between the first and second tests versus initial 6MWD among participants whom underwent repeat testing (n=56). Springer Nature. The 6-min walking distance (6MWD) test is a useful tool to obtain a measure of functional exercise capacity. 1979;47:128794. This is a quick and inexpensive measure of physical function, as it reflects the capacity to perform everyday activities. {645 }*{\text{ RSD}}$$, https://doi.org/10.1186/s12931-022-02003-y, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/. Cardiorespiratory fitness; Exercise test; Reference values. Am J Respir Crit Care Med. The 6-min walk distance in healthy subjects: reference standards from seven countries. A: Six-minute walk distance by number of self-reported days of exercise per week. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. Eur Respir J. Lines represent fitted spline regression, A: Six-minute walk distance by number of self-reported days of exercise per, MeSH Moreover, the test is frequently employed as an outcome measure for pulmonary and cardiovascular rehabilitation, and as a selection tool for pulmonary surgery candidates [4, 5]. Declaration of competing interest SJH reports no conflicts of interest. Observed (circle and triangles markers) and adjusted marginal mean (line) 6MWD by age in females and in males, Observed (circle and triangles markers) and adjusted marginal mean (line) 6MWD by weight and height in females and in males, Adjusted marginal mean 6MWD by age and height in males. Eur Respir J. 6-Minute Walk Test (6MWT) (applied to patients who have had lower Nixon PA, Joswiak ML, Fricker FJ. Breusch TS, Pagan AR. This can befound at: http://neuropt.org/practice-resources/anpt-clinical-practice-guidelines/core-outcome-measures-cpg This protocol includes standardized instructions, timing and examples of encouragementto provide during the test. Part of A taller height is associated with a longer pass, which may result in a longer distance travelled. Ramsey JB. Thorax. Zou H, Zhu X, Zhang J, Wang Y, Wu X, Liu F, Xie X, Chen X. PLoS One. 2002;19:815. We need to acknowledge the limits of the study. Previous evidence highlights the importance of using the 6MWT, in terms of its safety, reliability and validity properties, and usefulness in assessing functional assessment and is a powerful prognostic marker for functional capacity in both healthy and unhealthy individuals [6]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Pahor M, Guralnik JM, Ambrosius WT, Blair S, Bonds DE, Church TS, Espeland MA, Fielding RA, Gill TM, Groessl EJ, King AC, Kritchevsky SB, Manini TM, Mcdermott MM, Miller ME, Newman AB, Rejeski WJ, Sink KM, Williamson JD. All the assumption, including the level of Levens test of homogeneity, normal population distribution and data independency were met. 2013;187(4):3826. Second, none of the study has used a sample size calculation, which makes difficult to generalize the findings to the whole population of children. For each variable, we determined sex- and age-specific percentile values (5th, 15th, 25th, 50th, 75th, 85th and 95th) and used the Lambda (L), Mu (M) and Sigma (S) method, in which the optimal power to obtain normality is summarized by a smooth (L) curve and trends in the mean (M) and coefficient of variation (S) are similarly smoothed. Although its practical implications have been well-documented [16], little evidence has been provided for normative data in healthy children [17]. Finally, the 6MWT wasnt performed twice with a 30-min rest interval, as recommended by the ATS Committee [16]. PLOS ONE. This study has a few strengths. Six-minute walking test: normal reference values for Taiwanese children and adolescents. Next, all three curves (L, M and S) are summarized based on the power of age-specific BoxCox power transformations for normalizing the data [25]. 2014;311:2387. Each regression considered the 6MWD as dependent variable, and age, sex, smoking habits, BMI and one at a time other potentially relevant factors (such as reported cardiovascular diseases, arthritis, diabetes, cancer, hypertension and obstructive sleep apnoea syndrome) as independent variables. The 6MWD test has advantages over laboratory-based tests on exercise tolerance since it more closely reflects the ability to perform daily life activities and does not require sophisticated and expensive equipment [1,2,3]. A recent review of functional walking tests concluded that "the 6MWT is easy to administer, better tolerated, and more reflective of activities of daily living than the other walk tests" (9). An Initial Assessment of the Decline With Age for the 6-minute Walk The R squared values of these models were 0.2381 in women and 0.1592 in men. Participants: From January 2017 to January 2021, a total of 525 patients (431 men, 94 women . Changes in the 6 minute walk distance (6MWD) are used to evaluate the efficacy of therapeutic Also, reference equations with sociodemographic, anthropological and health-related indicators for cross-correlation and predictive purposes need to be developed, in order to compare the data between the countries. The mean walking speed for boys and girls was 985m/min and 916m/min. Marcon A, Girardi P, Ferrari M, Olivieri M, Accordini S, Bombieri C, Bortolami O, Braggion M, Cappa V, Cazzoletti L, Locatelli F, Nicolis M, Perbellini L, Sembeni S, Verlato G, Zanolin ME, de Marco R. Mild asthma and chronic bronchitis seem to influence functional exercise capacity: a multi-case control study. 2013;24(3):219. By using this website, you agree to our PubMed The negative influence of age is evident from around 40years of age and appears to be even more important as age increases, both in females and males. The main purpose of the study was to create sex-specific and age-specific normative data for the 6MWT in a large sample of children aged between 11 and 14years. Cookies policy. Our final sample was comprised of 4352 children (mean ageSD=121years, mean height=15610cm, mean weight=4711kg, mean body-mass index=193kg/m2; 66% of girls). official website and that any information you provide is encrypted 2 by height and weight, in females and in males separately. Older boys and girls performed better, compared to their younger counterparts (p for age<0.001). Respir Care. Briefly, in stage 1, new random samples or pre-existing randomly sampled cohorts from the general population (2085years of age, male/female=1/1) were mailed a screening questionnaire on respiratory symptoms [17]. PubMedGoogle Scholar. [35] reported that poor performance during the 6-min walk was significantly associated with reduced physical activity in a study of 775 individuals aged 3090years. Background: The six-minute walk test (6MWT) is a simple, low tech, safe and well established, self-paced assessment tool to quantify functional exercise capacity in adults. Age Matched Norms: 6 Minute Walk test Age in years Distance in feet Men Women 60-64 1830-2205 1635-1980 65-69 1680-2100 1500-1905 PubMed Stenholm S, Koster A, Valkeinen H, Patel KV, Bandinelli S, Guralnik JM, Ferrucci L. Association of physical activity history with physical function and mortality in old age. Google Scholar. Kanburoglu MK, Ozdemir FM, Ozkan S, Tunaoglu FS. The two-way interaction age-height and age-weight and the quadratic terms of weight and height were also tested for inclusion separately in each model. The reference equations were 6MWD=8.10*age+1.61*heightcm0.99*weightkg+22.58*active0.10*age2+222.55 for females (R squared=0.238) and 6MWD=26.80*age+8.46*heightcm0.45*weightkg2.54*active0.06*age20.13*age*heightcm890.18 for males (R squared=0.159), where active is 1 when the subject is physically active, 0 otherwise. Pediatr Pulmonol. 1989;44:4029. The linear regression model fitted to data for females (n=287) is presented in Table 3. The GEIRD study was funded by the Cariverona foundation (Bando 2006), the Italian Ministry of Health (RF-2009-1471235), Chiesi Farmaceutici SpA, and the Agenzia Italiana del Farmaco (AIFA). May 14, 2021 Photo: Stocksy / Raymond Forbes Photography T he 6-minute walk test (6MWT) is a widely available, easy-to-reproduce, and well-tolerated test that physicians use to evaluate. CAS Eur Respir J. Furthermore, we found evidence that the relationship between age and the distance walked is not linear but is better represented adding a quadratic term, and an interaction between age and height is present in males. World Appl Sci J. Body-mass index was calculated by using the following formula: weight (kg)/height (m2). 2015;37(11):921-7. doi: 10.3109/09638288.2014.948136. Before Federal government websites often end in .gov or .mil. ATS Statement | Guidelines for the Six-Minute Walk Test | American Gene Environment Interaction in Respiratory Diseases. Objective: To establish an initial assessment of the decline with age for the 6-minute walk test (6MWT) in patients with chronic obstructive pulmonary disease (COPD) in Chinese older adults. J Pediatr. VP conducted the study. 2013;54(2):12630. 2015;31(3):193201. Troosters T, Gosselink R, Decramer M. Six minute walking distance in healthy elderly subjects. Significant differences between sex (F1,7=144.05, p<0.001), age (F3,7=92.68, p<0.001) and sex*age interaction (F3,7=5.50, p<0.001) were observed. 1983;286:1713. This can be used to aid in the analysis of cardiopulmonary fitness, measure gait speed, reflect on participants' activities of daily living, and help to measure mobility). Chetta A, Zanini A, Pisi G, Aiello M, Tzani P, Neri M, Olivieri D. Reference values for the 6-min walk test in healthy subjects 2050 years old. Guyatt GH, Sullivan MJ, Thompson PJ, Fallen EL, Pugsley SO, Taylor DW, Berman LB. 2005;81:13304. Normative values for the 6MWT are presented in Table 2. https://www.dzs.hr/Hrv_Eng/publication/2020/08-01-02_01_2020.htm. Phys Ther. Bookshelf The 6MWT was significantly correlated with age (r=0.24, 95% CI 0.210.26, p<0.001), height (r=0.09, 95% CI 0.060.12, p<0.001), weight (r=0.13, 95% CI0.16 to0.10, p<0.001) and body-mass index (r=0.26, 95% CI0.29 to0.23, p<0.001). Keppler SE, Muir N. Reference values on the 6-minute walk test for children living in the United States. All analyses were performed in Statistical Packages for Social Sciences version 24. Moreover, previous work has shown a relationship between physical activity and physical performance [33, 34]. It is possible that we failed to consider other potential sources of variability. The 6-min walk test (6MWT) is a commonly used test for the objective assessment of functional exercise capacity for the management of patients with moderate-to-severe pulmonary disease. The authors have determined the lower limits of the norm, which are: 6MWD is the 6 minute walk distance expressed in meters. CAS Indian J Pediatr. Chest. To calculate correlations between all the study variables, we used Pearson coefficient of correlation (r). If we consider only subjects over 40years of age, Enright and Sherrill equations underestimate the 6MWD in our sample by 6m in females and overestimate it by 13m in males. 2019;25:839. The contact for this request is the corresponding author, and the request will be forwarded to the Steering Committee of the GEIRD study that will evaluate the request and decide whether to approve it. One source of variance may be the different attitudes and the mood of the participants [36, 37]. 1992;47:7819. Culver BH. This model was compared to existing prediction equations. The 6-minute walk: a new measure of exercise capacity in patients with chronic heart failure. Backmann T, Maribo T, Zwisler AD, Davidsen JR, Rottmann N. Front Rehabil Sci. Correspondence to However, little evidence has been provided regarding population-based normal data in healthy children. Lammers AE, Hislop AA, Flynn Y, Haworth SG. the 6MWD) in meters. Reference Equations for the Six-Minute Walk Distance in the Healthy Chinese Han Population, Aged 18-30 Years. Third, the distance covered was measured only once for each child, providing no information about the testretest reliability for the studied sample. Several studies have been conducted in healthy adults over the last decades to provide reference values for the 6MWD. The 6 minute walk test calculator provides reference values for the distance an adult should walk during six minutes. The 6-minute walk test: normal values for children of 4-11 years of age Effect of attitudes and beliefs on exercise tolerance in chronic bronchitis. Google Scholar. Respir Res 23, 83 (2022). J Pediatr. Zou H, Zhang J, Chen X, Wang Y, Lin W, Lin J, Chen H, Pan J. BMC Pulm Med. Prediction models for six-minute walk distance versus age in the study population. Finally, height squared and weight squared were included in the models one at a time, if the Ramsey regression specification-error test for omitted variables was significant [24]. Particularly, Hall et al. The majority of these were performed on a low number of subjects (i.e. The subjects underwent lung function tests according to ATS/ERS guidelines [18], with reference values obtained by Quanjer [19]. The mean distance walked in 6 min was 57693m in boys and 54592m in girls, respectively. Int Arch Allergy Immunol. Specifically, a study by Cacau et al. The subjects of shorter stature appear to achieve the best physical performance expressed by 6MWD between 55 and 60years, followed by a slow decline in the distance covered. However, this study is not without limitation. Respiratory Research The six-minute-walk test (6MWT) provides information on daily physical performance. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Reference values for the 6-minute walk test in healthy - PubMed The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request. How should the lower limit of the normal range be defined? Figure1 shows the observed and adjusted marginal mean 6MWD by age, and Fig. J R Stat Soc Ser B. The six-minute walk test (6MWT) has become a widely used measure for assessing functional exercise capacity at submaximal level [1, 2]. The significant contribution of weight is in partial agreement with the findings of Enright [14], Trooster [8], Casanova [12], Zou [11], Oliveira [13], suggesting that when 6MWDs are reported in future studies, they should also be corrected for weight. Overweight and obesity increase the workload for a certain amount of exercise, thus explainingthe shorter distance travelled by women with higher body weight. Kadikar A, Maurer J, Kesten S. The six-minute walk test: a guide to assessment for lung transplantation. Furthermore, participants were generally recruited among students, employees and relatives [10,11,12,13], while only one study considered a sample from the general population [14]. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. 2013;17:55663. Comparison of six-minute walk test in children with moderate/severe asthma with reference values for healthy children. 2022 Dec;269(12):6555-6565. doi: 10.1007/s00415-022-11324-3. The final sample of 100 children included 26 children who completed the 6MWT as part of a study to compare gross motor efficiency and functional capacity in children . ELB has served as a consultant for Hovione Pharmaceuticals. For example, lean body mass, a parameter known to predict exercise capacity in healthy subjects, has not been measured [38]. Several studies have demonstrated the degradation of performance on the 6MW with increasing age. Age, height and weight were centred separately in males and females. Casanova C, Celli BR, Barria P, Casas A, Cote C, de Torres JP, et al. 2018;13(10):e0205792. Morgan AD, Peck DF, Buchanan DR, McHardy GJ. doi: 10.1371/journal.pone.0184669. CAS Tests for specification errors in classical linear least-squares regression analysis. The 6MWT protocol was developed according to the American Thoracic Society guidelines (2002) [23]. The impact of the health status on the 6MWT-distance in elderly, however, remains unclear, reducing its value in clinical settings. 2001;119:25670. 1, 2, 3 Despite the popularity of the 6MWT there is limited data relating six minute walk distance (6MWD) in patients with lung disease to that of healthy. Now we can check if this result falls into 6 minute walk test norm: The patient result of 432 meters is above the lower limit. DSilva C, Vaishali K, Venkatesan P. Six-minute walk test-normal values of school children aged 712 y in India: a cross-sectional study. 1996;129:3626. Terms and Conditions, Saad HB, Prefaut C, Missaoui R, Mohamed IH, Tabka Z, Hayot M. Reference equation for 6-min walk distance in healthy North African children 616 years old. The LMS method for constructing normalized growth standards. 1997;16:3139. Exercise testing and training in children with congenital heart disease. A Mixed Methods Study of Functioning and Rehabilitation Needs Following COVID-19. Age, sex, height, weight and physical activity with age-to-weight interaction in males, were the predictors of the 6MWD. 2005;171(6):5917. 2017 Aug 29;17(1):119. doi: 10.1186/s12890-017-0461-z. Introduction: The six-minute walk test (6MWT) is a widely used measurement of exercise capacity in many conditions that affect young adults. ATS Statement. Particularly, the lower lean mass in women (which is a marker of muscle mass [28]), would make them less tolerant of the weight-related increase in load. Cite this article. 21 Nov 2018: Vandoni M, Correale L, Puci MV, Galvani C, Codella R, et al. Article Height and weight were objectively measured using portable stadiometer and digital scale with a precision of 0.1mm and 0.1kg. PDF 6 Minute Walk Test (6 MWT) - cpb-us-w2.wpmucdn.com PMC 2011;37:1506. Springer Nature. Reference values for the 6-min walk test in healthy subjects 2050 years old. The 6 minute walk test (6MWT) assesses distance walked over 6 minutes as a sub-maximal test of aerobic capacity/endurance. Thorax. Can Med Assoc J. It is described as the distance person can walk at self-paced speed over the period of 6 min [3,4,5]. Thus, we considered 701 subjects for the subsequent analysis aimed to define the healthy group. Statistical methods for social scientists. Butland RJA, Pang J, Gross ER, Woodcock AA, Geddes DM. Inspiratory-to-total lung capacity ratio predicts mortality in patients with chronic obstructive pulmonary disease. Our 6 minute walk test calculator has a built-in converter. Int J Environ Res Public Health. Reference values for the six-minute walk test in healthy children and adolescents: a systematic review. Your US state privacy rights, Specifically, it reviews indications, details factors that influence results, presents a brief step-by-step protocol, outlines safety measures, describes proper patient preparation and procedures, and offers guidelines for clinical interpretation of results. Multiple regression analysis showed that sex (unstandardized coefficient=0.81.7, 95% CI92.8 to70.5, p<0.001), age (unstandardized coefficient=62.0, 95% CI 56.068.1, p<0.001), height (unstandardized coefficient=3.0, 95% CI 2.13.8, p<0.001) and weight (unstandardized coefficient=7.5, 95% CI8.2 to6.8, p<0.001) entered simultaneously into the model were significantly associated with the 6MWT (R=0.44, R2=19%, standard error of estimates=168.5m, p<0.001). 6MWD: 6-minute walking distance; 6MWT: 6-minute walk test; BMI: Body mass index; BP: Blood pressure; DW: Durbin-Watson test; HR: Heart Rate; MAP: Mean arterial pressure; PAS: Physical activity score; SD: Standard Deviation; SpO2: Peripheral oxygen saturation. Chest. J Heart Lung Transplant. The 6-min walk test (6MWT) is a commonly used clinical assessment of exercise capacity in patients with cardiopulmonary or neuromuscular disease, but normal values are lacking for young adults, who are frequent subjects of testing. The 6-minute walk test: normal values for children of 4-11 years of age Am J Respir Crit Care Med. 2011;43:133459. Analyses and procedures performed in the study were anonymous and conducted in accordance with the Declaration of Helsinki regulations. The mean value for distance covered in 6 min for the aforementioned studies ranged between 47059m and 707102 [2, 20]. We wish to thank all members participating in the GEIRD study, our research is based on the underlying research conducted by their hard work. Age was self-reported. Let's check if that's the norm. Vandoni M, Correale L, Puci MV, Galvani C, Codella R, Togni F, et al. 6-Minute Walk Test (6MWT) Calculator Imperial Metric Male Female Weight Weight in Pound Height The reference equations for females and males were calculated considering that the estimates of the coefficients have been obtained with centred variables. The six minute walk test (6MWT) is the most frequently used exercise test in pulmonary rehabilitation and is considered to provide a reliable and valid measure of functional exercise capacity. PDF Technical Standard for Functional Exercise Testing - 6 Minute Walk Test Therefore, the main purpose of the study was to create sex-specific and age-specific normative data for the 6MWT in a large sample of children. LC, MEZ, MO, GV and MF contributed to the data collection. The purpose of this study was to determine the reference equations to predict the 6MWD in a large Italian population sample of healthy adults of a wide age range. Epub 2018 Jul 3. We calculated the 5th percentile lower limit of normal (LLN) using the estimated reference equations for 6MWD; the calculated LLN is: where RSD is the residual standard deviation of the estimated regression [27].